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临床试验/CTRI/2024/03/064326
CTRI/2024/03/064326尚未招募不适用

Association of deha prakriti with neurophysiological parameters with respect to Ulnar nerve in young and middle aged healthy volunteers-an observation Study

Central Council for Research in Ayurvedic Sciences1 个研究点 分布在 1 个国家目标入组 213 人开始时间: 2024年3月27日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
213
试验地点
1
主要终点
1. To study the co-relation between the Deha Prakriti (body genetic constitution) and neuro-physiological parameters, Nerve conduction velocity of an individual.

研究概览

简要总结

Introduction: Prakriti is a unique concept of Ayurveda which emphasises on the personalised treatment approach of individuals. Prakriti (body constitution) is of seven types depending on the permutation and combination of doshas attributes. Each Prakriti have their unique features and vary in anatomical features, metabolic rate, pace of activity, temperaments, habits. The vata dosha with chala guna(attribute) has fast movements (muscular, nervous), the pitta dosha with tikshna, ushna guna is responsible for cellular digestion and metabolism, the kapha dosha causing anabolic and synthetic functions represents the manda guna. The clinical significance of these guna can be co-related with the range of nerve conduction.1,2 This study aims to define scientific understanding of dosha gunas in specific prakriti and further document  the classical Ayurveda concepts in this contemporary era of research and technology.

Nerve Conduction is one of the novel areas which can be studied in prakriti types. Myelinated nerve fibres are wrapped by lipoprotein membranes of myelin are integrated with subsets of proteins specifically in each compartment to shape the physiological behaviour of these nerve fibres which is affected by genetics.3 For ex: a person with a Vata- Prakriti may have a predisposition to nervous system disorders, while a person with a Pitta- Prakriti may be more prone to inflammation-related issues that can affect nerve function. The normal values of NCV are 50-70 m/sec, the NCV of nerve may vary according to genetics. Nerve conduction studies assist in the evaluation of predisposition of neuromuscular diseases by providing a physiologic assessment of the peripheral nerve. Motor nerve conduction studies assess motor axons by selectively recording muscle responses to nerve stimulation. This study aims to find the association between deha prakriti type and neuro-physiological parameters  in ulnar nerve.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • The healthy volunteers of age group of 18-60 years who willingly give their consent for prakriti pariksha and neuro-physiological tests will be included in the study.

排除标准

  • Subjects below 18 yrs and above 60 yrs.
  • Subjects with history of neuro-muscular disorders, psychiatric medicines, diabetes, hypothyroidism, hyperthyroidism and any other illness which may affect the neurological functions will not be included in the study.

结局指标

主要结局

1. To study the co-relation between the Deha Prakriti (body genetic constitution) and neuro-physiological parameters, Nerve conduction velocity of an individual.

时间窗: 1.BASELINE: RESEARCH PROTOCOL DEVELOPMENT, SAMPLE SIZE ESTIMATION, CTRI REGISTRATION | CASE PERFORMA, | 4WEEKS :TRAINING IN PRAKRITI ASSESMENT AND NERVE CONDUCTION TESTS AND DATA COLLECTION | 8WEEKS: DATA COLLECTION AND DATA ANALYSIS

次要结局

  • This study will co-relate the prevalence of nerve disorders with Prakriti types(1. after data analysis the nerve conduction in vata prakriti, pitta prakriti and kapha prakriti healthy individuals will be graded. 5-6 month)

研究者

申办方类型
Government funding agency
责任方
Principal Investigator
主要研究者

Shrutika V Patankar

KAHERs Shri BMK Ayurved mahavidyalay,Belagavi.

研究点 (1)

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