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The Impact of the Human Papilloma Virus in Pediatric Chronic Kidney Disease, Dialysis, and Transplant Patients

Completed
Conditions
Chronic Kidney Disease
Dialysis
Interventions
Registration Number
NCT00767897
Lead Sponsor
Indiana University
Brief Summary

The proposed study is a pilot study and a first step towards developing an optimized HPV vaccination strategy for girls who have CKD, or are on dialysis or have a kidney transplant.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
72
Inclusion Criteria
  • 9-18-year-old girls who have CKD stages 3 or 4 (Glomerular filtration rates 15-59 mL/min/1.73m2).
  • 9-18-year-old girls who are on dialysis.
  • 9-18-year-old girls who have had a functioning kidney transplant for longer than 6 months and are on the same immunosuppression regimen.
  • Healthy 9-18-year-old girls
Exclusion Criteria
  • Pregnancy, fever, allergy to any vaccine component, any immune disorder and any blood product received in the previous 6 months.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
CKD stage 3 or 4Human Papillomavirus VaccineGirls and Boys age 9-18 with CKD stage 3 or 4
On dialysisHuman Papillomavirus VaccineGirls and Boys age 9-18 who are on dialysis
TransplantedHuman Papillomavirus VaccineGirls and Boys age 9-18 who have had a functioning kidney transplant for longer than 6 months and are on the same immunosuppression regimen.
HealthyHuman Papillomavirus VaccineGirls and Boys age 9-18
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Indiana University/Riley Children's Hospital

🇺🇸

Indianapolis, Indiana, United States

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