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Photodynamische Diagnostik mit 5-Aminolävulinsäure zur Beurteilung der intraoperativen Absetzungsränder im Rahmen der radikalen Prostatovesikulektomie bei Patienten mit einem Prostatakarzinom - Photodynamische Diagnostik beim Prostatakarzinom mit 5-ALA

Conditions
Patients with prostate carinoma who will undergo radical prostatectomy.
MedDRA version: 9.1Level: LLTClassification code 10036921Term: Prostate carcinoma
Registration Number
EUCTR2005-004406-93-DE
Lead Sponsor
Klinikum der Universität München
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

Patients with histologically proven prostate caricinoma.
Indication for radical prostatectomy.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Renal insufficiency.
Porphyria or allergy to porphyrines.
Hepatic insufficiency.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: Intraoperative investigation of surgical margins for residual tumor.;Secondary Objective: Practicability of PDD in the open vs. laparoscopic/extraperitoneal endoscopic operation technique.<br>PPIX-accumulation in tumors of different differentiation grade.;Primary end point(s): Absence or adsence of fluorescence in positive or negative surgical margins, as well as concordance of fluorescing areas with histological findings.
Secondary Outcome Measures
NameTimeMethod
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