Exercise-based Cardiac Rehabilitation
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Exercise
- Sponsor
- University of Isfahan
- Enrollment
- 60
- Primary Endpoint
- Effect of Exercise-based cardiac rehabilitation on lipids was measured by ELISA method
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
This study aimed to determine if eight-weeks of exercise-based cardiac rehabilitation could improve adiponectin and cardiovascular disease risk factors in overweight coronary heart disease patients. Patients were included in the study if: they were approved to do so following a physical, physiological and psychological test; did not take part in regular physical activity; had stable heart failure for at least 3 months. Exclusion criteria included: a history of surgery within the preceding 4 months; had an unstable angina, acute phase of myocardial infarction, and/or unstable arrhythmia; had obstructive cardiomyopathy, exercise-induced ischemia or arrhythmias, uncontrolled arrhythmias, resting blood pressure more than 200/120 millimeters mercury, aortic stenosis, and/or peripheral artery disease; exercise limitations due to neuromuscular and/or musculoskeletal disease; had any health problems that prevented maximum effort on the treadmill test. Target population included of all patients with a history of myocardial infarction and diagnosis of congestive heart failure who were referred to Isfahan Cardiovascular Research Centre. 60overweight coronary heart disease patients were randomly assigned to either an eight-week, three times weekly exercise group (n=30), or a non-exercising control group (n=30). Exercise sessions took place at 60-85% of maximal heart rate, lasted 45-60 minutes and included a 10-minute warm-up, 40 minutes of aerobic exercises, consisting of stationary cycling, walking and/or jogging, flexibility, balance exercises, and weight-bearing activity and a 10-minute cool-down.
Investigators
Prof.Mehdi Kargarfard
Professor Mehdi Kargarfard
University of Isfahan
Eligibility Criteria
Inclusion Criteria
- •they were approved to do so following a physical, physiological and psychological test; resided and worked in the city of Isfahan; did not take part in regular physical activity; had stable heart failure for at least 3 months.
Exclusion Criteria
- •a history of surgery within the preceding 4 months
- •had an unstable angina, acute phase of myocardial infarction (MI), and/or unstable arrhythmia
- •had obstructive cardiomyopathy, exercise-induced ischemia or arrhythmias, uncontrolled arrhythmias, resting blood pressure more than 200/120 millimeters mercury (mmHg), aortic stenosis, and/or peripheral artery disease
- •exercise limitations due to neuromuscular and/or musculoskeletal disease, such as any type of orthopedic, low back pain, bone fracture of less than 6 months
- •uncontrolled systemic disease, such as DM; were 75 years or older
- •had any health problems that prevented maximum effort on the treadmill test
- •unable to answer the screening questionnaires assessing depression and anxiety.
Outcomes
Primary Outcomes
Effect of Exercise-based cardiac rehabilitation on lipids was measured by ELISA method
Time Frame: up to 8 weeks
Effect of Exercise-based cardiac rehabilitation on Serum levels of adiponectin was measured by ELISA method
Time Frame: up to 8 weeks
Exercise sessions took place at 60-85% of maximal heart rate, lasted 45-60 minutes.
Secondary Outcomes
- Effect of Exercise-based cardiac rehabilitation on height was measured(up to 8 weks)
- Effect of Exercise-based cardiac rehabilitation on weight was measured(up to 8 weks)