Spinal Bupivacaine/Morphine in laparoscopic gastro-intestinal surgery
Phase 3
Completed
- Conditions
- Post-operative painwound pain10017998
- Registration Number
- NL-OMON41666
- Lead Sponsor
- Maasstad Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Laparoscopic Gastro-intestinal surgery
Exclusion Criteria
Bariatric surgery, rectal surgery, kidney-failure, Aorta-valve stenosis, coagulation disorders, emergency surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>elective laparoscopic gastro-intestinal surgery in adults</p><br>
- Secondary Outcome Measures
Name Time Method <p>Opioid-use in the post-operative phase, side-effects of opioids, mobilisation,<br /><br>, patient-satisfactory, difficulty of surgery, compliance of the abdominal wall<br /><br>during surgery and NK-cell activity</p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie bupivacaine/morphine spinal analgesia for post-operative pain?
How does spinal bupivacaine/morphine compare to systemic opioids in managing laparoscopic surgery wound pain?
Are there specific biomarkers that predict response to spinal bupivacaine/morphine in gastrointestinal surgery patients?
What are the potential adverse events associated with spinal bupivacaine/morphine administration in phase III trials?
What combination analgesic strategies are being explored alongside spinal bupivacaine/morphine for enhanced post-operative pain management?