Spinal Bupivacaine/Morphine in Laparoscopic Gastro-intestinal Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Spinal injection bupivacaine/morphine
- Conditions
- Spinal Bupivacaine/Morphine in Laparoscopic Surgery
- Sponsor
- Maasstad Hospital
- Enrollment
- 56
- Locations
- 1
- Primary Endpoint
- Duration of hospital stay
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.
Detailed Description
We expect that in laparoscopic gastro-intestinal surgery, a single shot spinal with bupicavaine/morphine will result in a better analgesia in hte first 48 hours. Herby the patients will require less systemic opioids, which will decrease the side-effects. Furthermore, we expect the patients to recover quicker and show an earlier mobilisation and a shorter hospital stay. The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Laparoscopic Gastro-intestinal surgery
Exclusion Criteria
- •Bariatric surgery, gastric surgery, rectal surgery, kidney failure, aorta-valve stenosis, coagulation disorders, emergency surgery
Arms & Interventions
Spinal injection
Patients receive spinal injection Bupivacaine/Morphine
Intervention: Spinal injection bupivacaine/morphine
Subcutaneum injection
Placebo subcutaneum injections
Intervention: subcutaneum injection lidocaine
Outcomes
Primary Outcomes
Duration of hospital stay
Time Frame: first 48 hours
Secondary Outcomes
- patient-satisfactory on a 4-point scale(120 hours/ 5 days)
- time to mobilisation(120 hours/ 5 days)
- time to bowel movement(120 hours/ 5 days)
- abdominal compliance during laparoscopy in L/mmHg(The compliance will be measured for the duration of the surgery, an expected average of 2 hours.)
- Difficulty of surgery(The difficulty of surgery will be measured for the duration of the surgery, an expected average of 2 hours)
- the occurence of side-effects (nausea, pruritus, drowsiness)(120 hours/ 5 days)
- use of piritramide by PCIA-pump in mg(48 hours)