Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique
Not Applicable
Completed
- Conditions
- Radiofrequency AblationHepatocellular Carcinoma
- Interventions
- Procedure: RFA
- Registration Number
- NCT03375281
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul national university hospital, Asan medical center, Samsung medical center, Kunkuk university hospital, St. mary's Seoul hospital
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
- Child-Pugh class A liver function
- 1 - 2.5 cm sized Single nodular HCC
- without history of previous HCC treatment or with evidence of no recurrence at least 2 years after previous HCC treatment
Exclusion Criteria
- more than 2 HCC
- tumor size larger than 2.5 cm
- Child-Pugh class B or C liver function
- invisible tumor even after real-time fusion US guidance
- accompanied by vascular invasion or distant metastasis
- presence of coagulopathy defined as platelet count < 50,000/mm3 and/or PT-INR > 50%
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description No touch group RFA RFA for small HCC would be done by using no touch technique
- Primary Outcome Measures
Name Time Method 1 year local tumor progression 1 year after procedure cumulative incidence of local tumor progression after RFA
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (5)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
KonKuk university hospital
🇰🇷Seoul, Korea, Republic of
Asan medical Center
🇰🇷Seoul, Korea, Republic of
Samsung medical center
🇰🇷Seoul, Korea, Republic of
Saint Mary Hospital
🇰🇷Seoul, Korea, Republic of