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Clinical Trials/NCT06377280
NCT06377280
Completed
Not Applicable

An Un-controlled, Prospective, Multi-center, Post Market Clinical Follow-up Investigation to Confirm Performance and Safety of Navina Mini, a New CE-marked Low-volume Transanal Irrigation (TAI) Device.

Wellspect HealthCare1 site in 1 country40 target enrollmentJanuary 18, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bowel Dysfunction
Sponsor
Wellspect HealthCare
Enrollment
40
Locations
1
Primary Endpoint
Patient satisfaction
Status
Completed
Last Updated
last year

Overview

Brief Summary

This is an un-controlled, prospective, multi center, post market clinical follow-up investigation that will enroll male and female subjects in need of bowel management with low-volume transanal irrigation (TAI) as judged by the investigator. A total of 40 investigational subjects in need of low-volume TAI will be recruited from 2-3 sites in Sweden and will be treated with Navina Mini as per product intended purpose and per instruction of use during a period of four weeks.

Participating subjects will perform three visits during the clinical investigation and will be followed for a total of four weeks. The first visit, Visit 1, will be performed at the investigational clinic to assess eligibility, collect demographics, baseline data and instruct how to use the device. Visit 2 will be performed after two weeks of treatment through telephone contact. The final visit, Visit 3, will be performed after additional two weeks of treatment, and can be performed either at the investigational clinic or through telephone contact.

Registry
clinicaltrials.gov
Start Date
January 18, 2024
End Date
December 13, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Signed informed consent
  • Anal incontinence or faecal outlet problems without any pathological obstruction in the ano-rectum.
  • Symptom duration of \> 6 months
  • Adult male and females \>18 years old
  • Patient can communicate in written and oral Swedish language

Exclusion Criteria

  • Subjects treated with high volume TAI i.e., volume \> 250 ml
  • Pregnancy at the time of enrollment
  • Participating in another clinical investigation interfering with this investigation
  • Subjects with active, symptomatic inflammatory bowel disease, radiation proctitis and or active perianal fistula disease
  • Rectal bleeding of uncertain origin or active hemorrhoidal bleeding
  • \< 6 months after anal or colorectal surgery
  • Ongoing anti-coagulant therapy (eg. NOACS, heparin, Warfarin)
  • Acute diverticulitis and diverticular abscess
  • Ischemic colitis
  • Colorectal cancer

Outcomes

Primary Outcomes

Patient satisfaction

Time Frame: 4 weeks

Patient Reported Outcome - Overall patient satisfaction when performing low- volume trans-anal irrigation measured with a 5-graded scale \[0 = Not at all satisfied, 1 = Not satisfied, 2 = Neither satisfied nor unsatisfied, 3=Satisfied, 4 = Very satisfied\]

Secondary Outcomes

  • Ease of handling(4 weeks)
  • Safety Outcome(4 weeks)
  • Assessment of clinical benefit(4 weeks)

Study Sites (1)

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