Comparison of the effects of Rivaroxaban and Apixaban with Heparin and Enoxaparin in patients undergoing gynecological oncological surgery.
Phase 2
Recruiting
- Conditions
- Women's cancers including: endometrium, ovary, cervix, vulva.Malignant neoplasm of uterus, part unspecified
- Registration Number
- IRCT20220211053991N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Age 18 to 70 years
Obtaining informed consent
Cancer disease
Exclusion Criteria
Liver failure
Deep vein thrombosis (DVT)
History of Gastrontestinal bleeding
Pregnancy
Taking other anticoagulants
Breast feeding
Post-transplant erythrocytosis (PTE) PTE disorders
Kidney failure (glomerular filtration rate (GFR) less than 30)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Shortness of breath. Timepoint: Before and after surgery. Method of measurement: Examination.
- Secondary Outcome Measures
Name Time Method Bleeding. Timepoint: Before and after surgery. Method of measurement: Examination.;Pain. Timepoint: Before and after surgery. Method of measurement: Examination.;Size of organ. Timepoint: Before and after surgery. Method of measurement: Examination.;Time to take the medicine. Timepoint: Before and after surgery. Method of measurement: Questionnaire.;Doppler ultrasound results. Timepoint: Before and after surgery. Method of measurement: ultrasound.;Swelling of the limbs. Timepoint: Before and after surgery. Method of measurement: Examination.