Assessment of Direct Oral Anticoagulant Use and Clinical Outcomes among Patients with Kidney Impairment at Faculty of Medicine Siriraj Hospital

Completed

• Conditions: Patients who were prescribed first DOACs between January 1, 2019 to December 31, 2020; Direct oral anticoagulant, dosing, kidney impairment

• Registration Number: TCTR20230703002
• Lead Sponsor: Faculty of Medicine Siriraj Hospital Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-07-03
• Study Completion: 2024-01-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

Adult patients with eGFR <60 mL/min/1.73 m2 assessed by CKD-EPI equation

Exclusion Criteria

Patients who lost follow-up during the study period, patients who do not have a baseline serum creatinine within 3 months, and patients unable to have serum creatinine monitored for 6 months after the previous visit.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The optimal dose of DOACs that complies with the prescribing information 12 months after first DOAC prescribing The proportion of appropriate DOAC dosing

Secondary Outcome Measures

Name	Time	Method
The consistency between the prescribed dose and the prescribing information 12 months after first DOAC prescribing The proportion of consistency between the prescribed dose and the prescribing information