Normoxic Challenges Utility to Evaluate Blood Loss

Terminated

• Conditions: Hemorrhage

• Registration Number: NCT03194581
• Lead Sponsor: Centro Hospitalar do Tâmega e Sousa

Brief Summary

This study will evaluate the impact of repeated normoxic challenges on cerebral oxygenation as a measure of the effect of blood loss on DO2 during surgical procedures.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-06-12
• Study First Submitted QC: 2017-06-19
• Study First Posted: 2017-06-21
• Study Start: 2017-10-01
• Primary Completion: 2018-09-30
• Study Completion: 2018-09-30
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-19
• Last Update Posted: 2022-03-22

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Elective surgery
• High risk of intraoperative blood loss
• General anaesthesia

Exclusion Criteria

• Respiratory insufficiency
• Ischemic heart disease
• Stroke
• ASA classification > 3
• Laparoscopic surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in cerebral regional oxygen saturation	Before and 3 minutes after normoxic challenges

Trial Locations

Locations (1)

Centro Hospitalar Tâmega e Sousa; 🇵🇹 Penafiel, Porto, Portugal