The effect of MitoQ supplementation on cycling performance in trained individuals
Not Applicable
- Conditions
- Exercise-induced oxidative stressPhysical Medicine / Rehabilitation - Other physical medicine / rehabilitation
- Registration Number
- ACTRN12619000451101
- Lead Sponsor
- niversity of Auckland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped early
- Sex
- Male
- Target Recruitment
- 21
Inclusion Criteria
Male
35-50 years
Cycle trained (at least 4 hours of cycling per week on average over the last 6 months)
Healthy
Exclusion Criteria
Allergies to nutritional supplement
Taking medications which may affect exercise responses
Any chronic or advance health conditions or injuries
Smoking
Antioxidant supplement intake within the previous 2 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to complete an 8 km cycling time trial on a stationary cycle ergometer[After an initial loading period, during which participants will cycle on a stationary cycle ergometer for 45 minutes at 70% of their peak power output, time to complete an 8 km cycling time trial will be recorded following 4 weeks of supplementation with MitoQ and 4 weeks of placebo treatment.]
- Secondary Outcome Measures
Name Time Method Markers of exercise-induced oxidative stress including GSH/GSSG ratio and F2-isoprostanes will be measured in whole blood and plasma using biochemical assays. This is a composite secondary outcome.[Markers of oxidative stress including GSH/GSSG ratio and F2-isoprotanes will be measured in plasma and whole blood immediately before exercise, immediately after completion of the 45 minute loading period at 70% of the participant's peak power output, and immediately after the completion of an 8 km time trial following 4 weeks of supplementation with MitoQ and 4 weeks placebo treatment.]