High dose simvastatin combined with standard chemotherapy in patients with refractory Multiple Myeloma: a phase II study

Phase 2

Completed

• Conditions: Multiple myeloma; Cancer; Myeloma

• Registration Number: ISRCTN85384018
• Lead Sponsor: niversity Medical Centre Utrecht (UMCU) (The Netherlands)

Brief Summary

2006 Protocol article in https://pubmed.ncbi.nlm.nih.gov/17107282/ Protocol 2007 Results article in https://doi.org/10.3324/haematol.12071 (added 27/10/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2006-09-14
• Study Start: 2007-06-27
• Last Update Posted: 8 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

1. Multiple myeloma patients
2. At least two cycles of chemotherapy with adriamycin and dexamethasone
3. Aged less than 75 years

Exclusion Criteria

1. Inadequate hepatic and renal function

Study & Design

• Study Type: Interventional
• Study Design: Not specified