Manipulation of Dietary Protein and the Anabolic Response

Not Applicable

Completed

• Conditions: Focus: Anabolic Response to Food Intake in Young Individuals; Condition Relevance: Skeletal Muscle Health, Sarcopenia

• Registration Number: NCT01820975
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-03-18
• Study First Submitted QC: 2013-03-26
• Study First Posted: 2013-03-29
• Study Start: 2013-04
• Primary Completion: 2015-03
• Status Verified: 2015-05
• Study Completion: 2017-02-01
• Last Update Submitted: 2017-03-21
• Last Update Posted: 2017-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 28

Inclusion Criteria

• Males
• Aged between 18-35 years
• Healthy, recreationally active
• BMI < 30 kg/m2

Exclusion Criteria

• Smoking
• Allergies to milk proteins (whey or casein)
• Vegetarians
• Diagnosed GI tract diseases
• Female
• Arthritic conditions
• A history of neuromuscular problems
• Previous participation in amino acid tracer studies
• Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Muscle protein fractional synthetic rate following protein ingestion	3 hours	The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.