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Clinical Trials/NCT03797755
NCT03797755UnknownNot Applicable

Prospective Observational Study of the Prognosis of Patients Having Palliative Radiotherapy

Tuen Mun Hospital1 site in 1 country450 target enrollmentStarted: January 1, 2019Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
450
Locations
1
Primary Endpoint
Overall Survival

Study Overview

Brief Summary

Many patients with incurable cancer will receive palliative oncological treatment before their death, and radiotherapy (RT) is an important element of this. The aim of palliative RT is to alleviate symptoms and improve quality of life. An accurate and practical survival prediction model for metastatic cancer patient receiving palliative RT can assist the decision making (ranging from best supportive treatment alone for expected short survival, to dose escalation for potential better disease control).

The available survival prediction models (such Survival Prediction Score using Number of Risk Factors by Chow et al and TEACHH model) have been developed in the Western world. We therefore perform a prospective observational study 1) to assess the overall survival of patients evaluated for palliative RT at a tertiary hospital in Hong Kong, and 2) to validate the prognostic score systems in our population.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • All adult patients with stage IV cancer who are referred for palliative RT in Tuen Mun Hospital, including both inpatients and outpatients.

Exclusion Criteria

  • Patients who have received palliative RT before (i.e. not the first course palliative RT), have non-metastatic disease, are misclassified as palliative patients.

Outcomes

Primary Outcomes

Overall Survival

Time Frame: 1 year

Overall Survival in the studied population

Secondary Outcomes

  • Overall Survival in Each Indication of Palliative Radiotherapy(3, 6, 9, 12 months)
  • Overall Survival by Survival Prediction Model (TEACHH)(3, 6, 9, 12 months)
  • Overall Survival by Survival Prediction Model (NRF)(3, 6, 9, 12 months)

Investigators

Sponsor Class
Other Gov
Responsible Party
Principal Investigator
Principal Investigator

Shing Fung Lee

Resident Specialist

Tuen Mun Hospital

Study Sites (1)

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