Prospective Observational Study of the Prognosis of Patients Having Palliative Radiotherapy
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Tuen Mun Hospital
- Enrollment
- 450
- Locations
- 1
- Primary Endpoint
- Overall Survival
Study Overview
Brief Summary
Many patients with incurable cancer will receive palliative oncological treatment before their death, and radiotherapy (RT) is an important element of this. The aim of palliative RT is to alleviate symptoms and improve quality of life. An accurate and practical survival prediction model for metastatic cancer patient receiving palliative RT can assist the decision making (ranging from best supportive treatment alone for expected short survival, to dose escalation for potential better disease control).
The available survival prediction models (such Survival Prediction Score using Number of Risk Factors by Chow et al and TEACHH model) have been developed in the Western world. We therefore perform a prospective observational study 1) to assess the overall survival of patients evaluated for palliative RT at a tertiary hospital in Hong Kong, and 2) to validate the prognostic score systems in our population.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All adult patients with stage IV cancer who are referred for palliative RT in Tuen Mun Hospital, including both inpatients and outpatients.
Exclusion Criteria
- •Patients who have received palliative RT before (i.e. not the first course palliative RT), have non-metastatic disease, are misclassified as palliative patients.
Outcomes
Primary Outcomes
Overall Survival
Time Frame: 1 year
Overall Survival in the studied population
Secondary Outcomes
- Overall Survival in Each Indication of Palliative Radiotherapy(3, 6, 9, 12 months)
- Overall Survival by Survival Prediction Model (TEACHH)(3, 6, 9, 12 months)
- Overall Survival by Survival Prediction Model (NRF)(3, 6, 9, 12 months)
Investigators
Shing Fung Lee
Resident Specialist
Tuen Mun Hospital
