A study to compare the characteristics of two durgs (hyperbaric (0.5%) Bupivacaine and hyperbaric (0.75%) Ropivacaine ) which is used for loss of pain sensation over lower half of body by giving injection in lower vertebral canal in Cesarean Section.
- Conditions
- Pregnancy, childbirth and the puerperium,
- Registration Number
- CTRI/2022/05/042898
- Lead Sponsor
- DR PRATIBHA JAIN SHAH
- Brief Summary
In this study we give one of the our study drug to pregnant patients for lscs in spinal anaesthesia.We use double blindtechnique .in which patient and investigator will be blind to study drug whichwill be given to patient .The drug will be prepared by an anaesthesiologistother than the principal investigator, who will be blinded to the studyprotocol and will not be involved in further data collection and assessment ofpatient . All patients will be informed and explained about the procedure .themultipara monitor will be attached to patients in supine position and baselinevital parameters such as BP, HR , RR and SpO2 will be recorded. An intravenousline will be established with 18 g cannula to preload the patient with ringerlactate solution at 10 ml /kg before the initiation of spinal block. Thenpremedication will be done with inj ondansetron 4mg iv .spinal anaesthesia willbe given at sitting position at the L3-L4 level identified by land marktechnique . with a 25-g Quincke’s spinal needle .our primary outcome is onsetof sensory block at the t10 level and secondary outcome are onset ofmotor block, duration of sensory & motor block.grade of sensory &motor block,duration of analgesia ,hemodynamic changes( BP ,HR ,RR, SpO2). sideeffects and complications(nausea, vomiting, hypotension, shivering ,respiratorydistress ) .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 80
- 1 ASA grade 2 Age between 18 to 40 yrs .
- 3 BMI <30 KG/M2 4 Height 150-170 cm.
- 5 Elective cesarean section under spinal anaesthesia.
- 2 Any neurological condition like demylinating lesions,increased intracranial tension, and head injuries .
- 3 Diabetes mellitus,hypertension,renal,hepatic ,pulmonary or pre-existing cardiac diseases(severe mitral stenosis or severe aortic stenosis).
- 4 Contraindication to spinal anaesthesia.
- 5 Chronic pain medication.
- 6 bleeding or coagulation disorders and those on anticoagulant therapy.
- 7 History to allergy of study drug.
- 8 Partial or failed Spinal anaesthesia .
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Onset of sensory block at the T10 level WITHIN 30 MIN after spinal anaesthesia for LSCS.
- Secondary Outcome Measures
Name Time Method 1 Onset of motor block. 2 Duration of sensory & motor block.
Trial Locations
- Locations (1)
Dr Bhim Rao Ambedkar Memorial Hospital ,Raipur
🇮🇳Raipur, CHHATTISGARH, India
Dr Bhim Rao Ambedkar Memorial Hospital ,Raipur🇮🇳Raipur, CHHATTISGARH, IndiaDr Mohammed Firoz SheikhPrincipal investigator8319824046firozsheikh78@gmail.com