Positron Emission Tomography for detection of histologic transformation of indolent non-Hodgkin*s lymphoma: a pilot study

Recruiting

• Conditions: follicular lymphoma; low grade lymphoma; 10025320

• Registration Number: NL-OMON32557
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 34

Inclusion Criteria

Inclusion criteria
1. Patients with newly diagnosed follicular lymphoma or newly diagnosed histological transformation of follicular lymphoma proven by histological examination.
2. Ann Arbor stage at diagnosis: II, III or IV.
3. at least one lesion > 2 cm diameter
4. After the diagnosis and before performing both PET scans they have not received any treatment.
5. Ability to remain supine for 60 min. (PET)
6. Written informed consent.

Exclusion Criteria

Exclusion criteria
1. Uncontrolled diabetes mellitus.
2. Physical inability to access PET facilities.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. detection rate (number of true positive PET lesions for either tracer, using<br /><br>CT as reference test)<br /><br>2. relative tracer uptake (SUV) for either tracer (lesion by lesion analysis,<br /><br>lesion with highest uptake of FDG or FLT)<br /><br>3. lowest and highest SUV for either tracer within one patient.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable.</p><br>