Comparison of two different doses of pre-operative nebulisation of magnesium sulphate in reducing the incidence of post operative sore throat following endotracheal intubation in patients undergoing surgery under general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- 1. Post operative sore throat at rest
研究概览
简要总结
In this study, we will compared two different doses of pre-operative nebulisation of magnesium sulphate in reducing the incidence of post operative sore throat following endotracheal intubation in patients undergoing surgery under general anaesthesia. Incidence of post operative sore throat will be examined at rest and on swallowing at different interval of times at 0hr, 2hrs, 4hrs, 6hrs, 10hrs and 24hrs. Apart from incidence of post operative sore throat, other laryngeal complaints such as cough, hoarseness of voice, nausea and vomiting, respiratory depression and hypotension will also examine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between 20 to 65 years, American society of anaesthesiologists grading 1 and 2, Mallampati scoring 1 and 2, duration of surgery more than 1 hour.
排除标准
- •Patient refusal, allergy to drugs, head and neck surgery, American society of anaesthesiologists grade 3 and 4, patients with upper respiratory tract infection, neuromuscular diseases, patients with nasal and throat pack, age less than 20yrs and more than 65years.
结局指标
主要结局
1. Post operative sore throat at rest
时间窗: 0hours, 2 hours, 4hours, 6hours, 10hours, 24hours
2. Post operative sore throat on swallowing
时间窗: 0hours, 2 hours, 4hours, 6hours, 10hours, 24hours
次要结局
- Laryngeal complaints such as cough, hoarseness of voice, nausea and vomiting, respiratory depression and hypotension(0hours, 2 hours, 4hours, 6hours, 10hours, 24hours)
研究者
Dr Khullar Kamnong
Sardar Patel Medical College