Postoperative Analgesic Effects of Dexmedetomidine Added to Bupivacaine for Transversus Abdominis Plane Block for Lower Abdominal Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- opioid consumption
研究概览
简要总结
the aim of this study is evaluate postoperative analgesic effects of dexmedetomidine added to bupivacaine on TAP block in patients undergoing lower abdominal surgery.
详细描述
TAP block is being used a method of multimodal balanced analgesia reduces postoperative pain, opioid requirement after surgery and adverse effect of opioid such as sedation, nausea vomiting and ileus. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 aged
- •patient undergoing lower abdominal surgery
排除标准
- •chronic opioid consumption
- •bupivacaine and dexmedetomidine allergies
- •coagulopathy
- •infection at the needle insertion side
- •chronic liver and kidney disease
研究组 & 干预措施
dexmedetomidine
100 mcg dexmedetomidine added to 0,5% 20 ml bupivacaine on TAP block
干预措施: Dexmedetomidine (Drug)
bupivacaine
0,5% 20 ml bupivacaine added 0.9% 1 ml serum physiologic on TAP block
干预措施: Bupivacaine (Drug)
serum phsyologic
0,9% 21 ml serum physiologic
干预措施: serum physiologic (Drug)
结局指标
主要结局
opioid consumption
时间窗: postoperative 1 day
patient controlled analgesia
次要结局
- visual analog scale(postoperative 1 day)
研究者
Recep Aksu
associated prof.
TC Erciyes University