Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane Block
Phase 4
Completed
- Conditions
- Pain
- Interventions
- Registration Number
- NCT02064530
- Lead Sponsor
- TC Erciyes University
- Brief Summary
the aim of this study is evaluate postoperative analgesic effects of dexmedetomidine added to bupivacaine on TAP block in patients undergoing lower abdominal surgery.
- Detailed Description
TAP block is being used a method of multimodal balanced analgesia reduces postoperative pain, opioid requirement after surgery and adverse effect of opioid such as sedation, nausea vomiting and ileus. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- ASA 1-2
- 18-65 aged
- patient undergoing lower abdominal surgery
Exclusion Criteria
- chronic opioid consumption
- bupivacaine and dexmedetomidine allergies
- coagulopathy
- infection at the needle insertion side
- chronic liver and kidney disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description bupivacaine Bupivacaine 0,5% 20 ml bupivacaine added 0.9% 1 ml serum physiologic on TAP block serum phsyologic serum physiologic 0,9% 21 ml serum physiologic dexmedetomidine Dexmedetomidine 100 mcg dexmedetomidine added to 0,5% 20 ml bupivacaine on TAP block
- Primary Outcome Measures
Name Time Method opioid consumption postoperative 1 day patient controlled analgesia
- Secondary Outcome Measures
Name Time Method visual analog scale postoperative 1 day
Trial Locations
- Locations (1)
Erciyes universty
🇹🇷Kayseri, Melikgazi, Turkey