Postoperative Analgesic Effects of Using Bupivacaine Alone or Added Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block in Thoracotomy
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- opioid consumption
研究概览
简要总结
we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy
详细描述
paravertebral block is commonly used in the treatment for acute and chronic pain.The duration of paravertebral block could theoretically be prolonged with neurolytic agents. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 aged
- •patient undergoing thoracotomy
排除标准
- •chronic opioid consumption
- •bupivacaine and dexmedetomidine allergies
- •coagulopathy
- •infection at the needle insertion side
- •chronic liver and kidney disease
研究组 & 干预措施
bupivacaine
0,5% 20 ml bupivacaine added 0.9% 1 ml serum physiologic on paravertebral block
干预措施: bupivacaine (Drug)
dexmedetomidine
100 mcg dexmedetomidine added to 0,5% 20 ml bupivacaine on paravertebral block
干预措施: dexmedetomidin (Drug)
serum phsyologic
0,9% 21 ml serum physiologic
干预措施: serum physiologic (Drug)
结局指标
主要结局
opioid consumption
时间窗: postoperative 24 hours
patient controlled analgesia
次要结局
- visual analog scale(postoperative 1 day)
研究者
Esra Nur Ünalan
resident
TC Erciyes University