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Postoperative Analgesic Effects of Using Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block

Phase 4
Completed
Conditions
Pain
Interventions
Registration Number
NCT02544893
Lead Sponsor
TC Erciyes University
Brief Summary

we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy

Detailed Description

paravertebral block is commonly used in the treatment for acute and chronic pain.The duration of paravertebral block could theoretically be prolonged with neurolytic agents. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
93
Inclusion Criteria
  • ASA 1-2
  • 18-65 aged
  • patient undergoing thoracotomy
Exclusion Criteria
  • chronic opioid consumption
  • bupivacaine and dexmedetomidine allergies
  • coagulopathy
  • infection at the needle insertion side
  • chronic liver and kidney disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
serum phsyologicserum physiologic0,9% 21 ml serum physiologic
bupivacainebupivacaine0,5% 20 ml bupivacaine added 0.9% 1 ml serum physiologic on paravertebral block
dexmedetomidinedexmedetomidin100 mcg dexmedetomidine added to 0,5% 20 ml bupivacaine on paravertebral block
Primary Outcome Measures
NameTimeMethod
opioid consumptionpostoperative 24 hours

patient controlled analgesia

Secondary Outcome Measures
NameTimeMethod
visual analog scalepostoperative 1 day

visual analog scale

Trial Locations

Locations (1)

Erciyes University Medicine Faculty

🇹🇷

Kayseri, Turkey

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