comparison of a new ventilation mode with conventional mode in patient requiring post operative ventilatory support after major abdominal surgery
Phase 4
- Conditions
- Health Condition 1: K319- Disease of stomach and duodenum, unspecified
- Registration Number
- CTRI/2024/03/063874
- Lead Sponsor
- All India Institute of Medical Sciences Patna Bihar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age greater than 18 years
All patients who have undergone abdominal surgeries of duration more than 3 hrs under GA and requiring post operative mechanical ventilation.
BMI less than 40 Kg per m2
ASA Grade I and II
Exclusion Criteria
Patients with obstructive or restrictive pulmonary disease
Patients for re exploration surgeries
Patient with Ejection fraction less than 30 percent
Patient with gross electrolyte disturbance
Patient with severe bleeding episode during surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure and compare the duration of mechanical ventilation in patients undergoing elective abdominal surgeries on adaptive supportive ventilation and conventional modes of ventilation ie SIMV ModeTimepoint: 1st Point: Intubation in OT <br/ ><br>2nd Point: End of Surgery which will indicate total duration of Surgery as end point in OT <br/ ><br>3nd Point: Transfer in ICU. <br/ ><br>4th Point: Removal of ET Tube ie Weaning. Duration of ventilation will be difference between admission time in ICU and extubation time ie known as weaning time from the entry into IC
- Secondary Outcome Measures
Name Time Method To measure the rate of extubation failure <br/ ><br>To measure the duration of ICU stay <br/ ><br>To compare the Tidal Volume, RR, Peak Inspiraotry Pressures, Peak Airway pressure at the time of randomisation versus just before extubation. <br/ ><br>To measure the PaO2 and FiO2 ratio just before and one hour after extubation <br/ ><br>To measure and compare the lactate levels one hour post extubation <br/ ><br>Timepoint: 1.5 years