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Effects of hypervolemia with hemodilution due to rapid fluid infusion on intracranial pressure in human volunteers

Not Applicable
Conditions
ot applicable(healthy male volunteers, opt-out)
Registration Number
JPRN-UMIN000044606
Lead Sponsor
ihon University
Brief Summary

An index of intracranial pressure increased significantly in infusion stages from preinfusion. Also, cerebral blood flow velocity in MCA increased significantly. However, No significant changes were observed in cerebral artery compliance or pulsatility index.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
12
Inclusion Criteria

Not provided

Exclusion Criteria

Participants who desire withdraw from the present study via opt-out.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
oninvasive ICP (nICP)
Secondary Outcome Measures
NameTimeMethod
Cerebral artery compliance CBF pulsatility index (PI)
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