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Clinical Trials/NCT01874912
NCT01874912CompletedNot Applicable

Human Irisin Concentration in Sarcopenia

Korea University1 site in 1 country406 target enrollmentStarted: November 2009Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
406
Locations
1
Primary Endpoint
Serum concentration of irisin in the subjects with sarcopenia
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross-sectional study, the researches investigated whether serum irisin levels are decreased in patients with sarcopenia compared with control subjects with normal muscle mass, and assessed the association between serum irisin levels and various metabolic parameters.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
20 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •20<age<80
  • •apparently healthy subjects

Exclusion Criteria

  • •a history of cardiovascular disease
  • •stage 2 hypertension
  • •malignancy
  • •severe renal or hepatic disease

Outcomes

Primary Outcomes

Serum concentration of irisin in the subjects with sarcopenia

Time Frame: 12 week

Secondary Outcomes

  • The relationship of serum irisin levels with lipid profiles(12 week)
  • The relationship of serum irisin levels with skeletal muscle mass index(12 wks)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

K. M. Choi

Professor

Korea University

Study Sites (1)

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