Human Irisin Concentration in Sarcopenia

Completed

• Conditions: Sarcopenia

• Registration Number: NCT01874912
• Lead Sponsor: Korea University

Brief Summary

Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross-sectional study, the researches investigated whether serum irisin levels are decreased in patients with sarcopenia compared with control subjects with normal muscle mass, and assessed the association between serum irisin levels and various metabolic parameters.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11
• Primary Completion: 2011-04
• Study Completion: 2011-04
• Status Verified: 2013-06
• Study First Submitted: 2013-06-03
• Study First Submitted QC: 2013-06-07
• Last Update Submitted: 2013-06-07
• Study First Posted: 2013-06-11
• Last Update Posted: 2013-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 406

Inclusion Criteria

• 20<age<80
• apparently healthy subjects

Exclusion Criteria

• a history of cardiovascular disease
• diabetes
• stage 2 hypertension
• malignancy
• severe renal or hepatic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum concentration of irisin in the subjects with sarcopenia	12 week

Secondary Outcome Measures

Name	Time	Method
The relationship of serum irisin levels with lipid profiles	12 week
The relationship of serum irisin levels with skeletal muscle mass index	12 wks

Trial Locations

Locations (1)

Korea University Guro Hospital; 🇰🇷 Seoul, Korea, Republic of