A study for evaluation of utility of indomethacin in tuberculous meningitis patients
Not Applicable
- Conditions
- Health Condition 1: null- Tuberculous Meningitis
- Registration Number
- CTRI/2018/02/011722
- Lead Sponsor
- Dr Ravi Uniyal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All Newly diagnosed cases of Tuberculos meningitis fulfilling consensus diagnostic criteria of TBM proposed by Marais et al (Lancet infect Dis 2010;10:803-12)
Exclusion Criteria
1.Patients already taking anti- tubercular drugs or steroids.
2.Patients with renal dysfunction (creatinine more than 1.5 mg/dl)
3.Human immunodeficiency virus disease
4.Patients/ attendants refusing consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure will be defined as the presence or non-occurrence of a paradoxical reaction in form of either clinical or radiological worseningTimepoint: Upto 6 months of randomization
- Secondary Outcome Measures
Name Time Method Secondary outcome will be assessed as disability by using modified rankin scale (MRS) <br/ ><br> <br/ ><br>Timepoint: at 1 month, 2 months, 3 months and 6 months