A study of effects of Calcium and Vitamin D supplementation on depletion of jaw bones in patients having all missing teeth.â??

Not Applicable

Completed

• Conditions: Health Condition 1: null- Completely edentulous patientsHealth Condition 2: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified

• Registration Number: CTRI/2017/09/009626
• Lead Sponsor: Indian Council of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

1.Non-smoking and non-alcohol drinking completely edentulous patients aged 60 years or above, who are not under medication for any oral, metabolic, skeletal, renal or endocrine disease or previous Calcium and/or Vitamin D supplementation.

2. All patients must have been edentulous for more than 1 year as the size of the residual ridge is reduced most rapidly in the first six months, which gradually decreases to a steady rate.

3.Class I and 2 edentulous subject with moderate alveolar ridge atrophy. (2)

4.Subjects with a philosophical mind set (MM House classification) as such patients recognize their responsibility of being an active partner in the treatment. They would probably be more compliant with recall appointments and denture wearing instructions.

Exclusion Criteria

1.Patients having smoking and/or alcohol drinking habit.

2.Patients on previous Calcium or Vitamin D supplements.

3.Previous denture wearers.

4.Mild or severely resorbed alveolar ridges, or ridges having a class II / III ridge relation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A positive outcome would be indicated by a decreased mean RRR (in mm) for the calcium and vitamin D supplementation group compared to the no supplementation group after 1 year, as measured on the CT scan.Timepoint: A positive outcome would be indicated by a decreased mean RRR (in mm) for the calcium and vitamin D supplementation group compared to the no supplementation group after 1 year, as measured on the CT scan.

Secondary Outcome Measures

Name	Time	Method
a record of residual ridge dimension and RRR in Indian patients (in mm) for the first time.Timepoint: 3 YEARS