Comparison between Dexmedetomidine and Magnesium sulphate for heart rate, blood pressure,intra-operative bleeding in functional endoscopic sinus surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: J339- Nasal polyp, unspecified
- Registration Number
- CTRI/2019/11/021910
- Lead Sponsor
- SMS Medical College Jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
body weight of 45 to 65 kg
ASA grade 1 and 2
undergoing elective resection of nasal polyp (duration 60-70 minutes)
Exclusion Criteria
history of allergy to these drugs
patients with pre existing bleeding and coagulation abnormalities
history of hypertension, CAD, renal and hepatic dysfunction
cerebral insufficiency
patients not willing to participate in study
orbital abscess
CSF leak with or without CSF rhinorrhea
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intraoperative SBP, DBP,MAP, HRTimepoint: base line <br/ ><br>after loading of study drug <br/ ><br>after induction <br/ ><br>1 min after intubation <br/ ><br>5 min after intubation <br/ ><br>10 min <br/ ><br>20 min <br/ ><br>30 min <br/ ><br>40 min <br/ ><br>50 min <br/ ><br>60 min <br/ ><br>70 min
- Secondary Outcome Measures
Name Time Method ASSESMENT OF INTRAOPERATIVE BLEEDING BY SURGEON <br/ ><br>EMERGENCE TIME <br/ ><br>TIME TO FIRST RESCUE ANALGESIC DEMANDTimepoint: EVERY TEN MINUTES