NCT01230879终止不适用
Study of Bronchoalveolar Lung Remodeling in Subjects From 60 Years Free of Progressive Lung Disease: Structure-function Analysis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 101
- 试验地点
- 2
- 主要终点
- Bronchial wall thickness
研究概览
简要总结
The aim of the study is to investigate the relationship between aging and morphological changes in the lung. 120 consecutive healthy volunteers over 60 years will be enrolled for this trial.
详细描述
Chest multidetector CT without injection and spirometry data will be obtained from a multicentric sample of individuals between 60 and 95 years of ageExclusion criteria were current smoking, history of smoking within the past 10 years, any known chronic or acute pulmonary disease. Individuals treated with Amiodarone, Bleomycin or methotrexate were excludedOutcome
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •People from 60 to 95 years old free from chest disease or history of chest disease
排除标准
- •Chronic cough
- •Sinonasal or chest infection during enrollment
- •Myocardial infarction.
- •Current smoker or past smoker with more than 10 pack year intoxication
结局指标
主要结局
Bronchial wall thickness
时间窗: 1 day
Bronchial wall thickness and remodeling associated with aging
次要结局
未报告次要终点
研究者
研究点 (2)
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