Astaxanthin and AGE-RAGE-Inflammation Axis

Phase 3

Recruiting

• Conditions: Polycystic Ovarian Syndrome.; Polycystic ovarian syndrome; E28.2

• Registration Number: IRCT20231028059882N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

Aged between 20 to 38 years old
Body mass index (BMI)= 20-30
Polycystic ovary syndrome (PCOS) diagnosis based on the Rotterdam criteria
Assisted reproductive technology (ART) candidate due to anovulatory infertility
Controlled ovulation stimulation (COS) by GnRH-Antagonist protocol

Exclusion Criteria

Pregnancy or abortion during the last year before the start of the study
History of other endocrinopathies such as adrenal hyperplasia, androgen-secreting tumors, hyperprolactinemia, thyroid dysfunction, diabetes, or impaired glucose tolerance
Coexistence of other causes of infertility (severe male factor, tubal factor, uterine factor, endometriosis, Asherman syndrome, diminished ovarian reserves, etc.)
Consumption of herbal or traditional medicine, antioxidant supplements, and vitamins within three months before the start of the study
Taking ovulation-induction drugs, hormonal agents, and metformin within three months before the start of the study

Study & Design

• Study Type: interventional
• Study Design: Not specified