Absorption of orange juice polyphenols

Completed

• Conditions: Bioavailabilty of orange juice polyphenols; Not Applicable

• Registration Number: ISRCTN04271658
• Lead Sponsor: The Coca-Cola Company (USA)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07-23
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

1. Healthy men and women.
2. Age 20-65 years

Exclusion Criteria

1. Smoking
2. On no medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The absolute bioavailability of orange juice phenolics will be the primary outcome of this study. Polyphenol metabolites and catabolites will be identified and quantified in urine collected over five time periods (0, 0-2, 2-5, 5-10 and 10-24 hours) following supplementation, using high-performance liquid chromatography coupled with tandem mass spectrometry and gas chromatography coupled with mass spectrometry.