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Virtual Physical Rehabilitation for Patients Living with Long COVID

Not Applicable
Completed
Conditions
Post COVID-19
COVID-19
Long COVID
Registration Number
NCT05298878
Lead Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Brief Summary

The purpose of this study is to investigate whether a timely, virtual home-based physical rehabilitation program for patients living with long COVID can improve functional mobility compared to usual care.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
132
Inclusion Criteria

(i) adult patients (18+ years old) who have had a confirmed or probable COVID-19 infection and who have self-reported persisting symptoms of either reduced mobility, muscle weakness, dyspnea, or fatigue;

(ii) participants must be technologically capable of connecting (either independently or through household members) with an online videoconferencing platform through an e-mail invitation; and

(iii) be able to collaborate with the research assistant to complete the virtual assessment sessions or have a family member available to help.

Exclusion Criteria

(i) pre-existing or newly identified severe cognitive impairment;

(ii) inability to speak or comprehend English or French;

(iii) known or self-reported acute and/or uncontrolled cardiac, musculoskeletal, or neurological condition that might render rehabilitation participation unsafe.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in the basic mobility domain of the Activity Measure for Post-Acute Care (AM-PAC)Baseline, Week 8 (up to 1 week), and at 6 months.

The AM-PAC is a validated, self-reported instrument assessing activity limitations based on the International Classification of Functioning, Disability, and Health (ICF). Each item is scored from 1 (unable to perform) to 4 (none or no difficulty) with lower scores indicating lower levels of function.

Secondary Outcome Measures
NameTimeMethod
Change in dyspneaBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the Transition Dyspnea Index.

Change in lower-body strengthBaseline, Week 8 (up to 1 week), and at 6 months.

The 1-minute sit-to-stand test (1-min STS) is feasible to use in hospital survivors of COVID-19. It is used to assess lower body-strength, exercise tolerance, and exertional desaturation. The score is the total number of stands within one minute.

Change in anxiety and depressionBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the Hospital Anxiety and Depression Scale.

Change in health state utilitiesBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the EuroQol 5-dimension 5-level Questionnaire (EQ-5D-5L).

Self-reported health service use30 days after the 8-week period.

Doctors visits, emergency department visits and hospital readmission etc.

Change in cognitive functionBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the AM-PAC Cognition Subscale.

Change in the degree of distress in response to traumaBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the Impact of Event Scale - Revised.

Change in fatigueBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the Fatigue Visual Analog Scale.

Change in health-related quality of lifeBaseline, Week 8 (up to 1 week), and at 6 months.

Measured by the Short Form 12-item Health Survey (SF-12).

Change in functional mobilityBaseline, Week 8 (up to 1 week), and at 6 months.

The fast-Timed-Up-and-Go test (TUG) assesses physical function and functional mobility. The score consists of the time taken to complete the test activity, in seconds.

Trial Locations

Locations (2)

McMaster University

🇨🇦

Hamilton, Ontario, Canada

Research Institute, McGill University Health Centre

🇨🇦

Montreal, Quebec, Canada

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