Virtual Physical Rehabilitation for Patients Living with Long COVID
- Conditions
- Post COVID-19COVID-19Long COVID
- Registration Number
- NCT05298878
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Brief Summary
The purpose of this study is to investigate whether a timely, virtual home-based physical rehabilitation program for patients living with long COVID can improve functional mobility compared to usual care.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 132
(i) adult patients (18+ years old) who have had a confirmed or probable COVID-19 infection and who have self-reported persisting symptoms of either reduced mobility, muscle weakness, dyspnea, or fatigue;
(ii) participants must be technologically capable of connecting (either independently or through household members) with an online videoconferencing platform through an e-mail invitation; and
(iii) be able to collaborate with the research assistant to complete the virtual assessment sessions or have a family member available to help.
(i) pre-existing or newly identified severe cognitive impairment;
(ii) inability to speak or comprehend English or French;
(iii) known or self-reported acute and/or uncontrolled cardiac, musculoskeletal, or neurological condition that might render rehabilitation participation unsafe.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change in the basic mobility domain of the Activity Measure for Post-Acute Care (AM-PAC) Baseline, Week 8 (up to 1 week), and at 6 months. The AM-PAC is a validated, self-reported instrument assessing activity limitations based on the International Classification of Functioning, Disability, and Health (ICF). Each item is scored from 1 (unable to perform) to 4 (none or no difficulty) with lower scores indicating lower levels of function.
- Secondary Outcome Measures
Name Time Method Change in dyspnea Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the Transition Dyspnea Index.
Change in lower-body strength Baseline, Week 8 (up to 1 week), and at 6 months. The 1-minute sit-to-stand test (1-min STS) is feasible to use in hospital survivors of COVID-19. It is used to assess lower body-strength, exercise tolerance, and exertional desaturation. The score is the total number of stands within one minute.
Change in anxiety and depression Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the Hospital Anxiety and Depression Scale.
Change in health state utilities Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the EuroQol 5-dimension 5-level Questionnaire (EQ-5D-5L).
Self-reported health service use 30 days after the 8-week period. Doctors visits, emergency department visits and hospital readmission etc.
Change in cognitive function Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the AM-PAC Cognition Subscale.
Change in the degree of distress in response to trauma Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the Impact of Event Scale - Revised.
Change in fatigue Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the Fatigue Visual Analog Scale.
Change in health-related quality of life Baseline, Week 8 (up to 1 week), and at 6 months. Measured by the Short Form 12-item Health Survey (SF-12).
Change in functional mobility Baseline, Week 8 (up to 1 week), and at 6 months. The fast-Timed-Up-and-Go test (TUG) assesses physical function and functional mobility. The score consists of the time taken to complete the test activity, in seconds.
Trial Locations
- Locations (2)
McMaster University
🇨🇦Hamilton, Ontario, Canada
Research Institute, McGill University Health Centre
🇨🇦Montreal, Quebec, Canada