Feasibility Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Semi-Structured Interview
研究概览
简要总结
This project seeks to evaluate the acceptability feasibility, practicality feasibility, and preliminary effect of combining transcranial direct current stimulation (tDCS) and metacognitive strategy training (MCST) in individuals with chronic stroke.
详细描述
Currently seven million people are living in the United States post stroke, making stroke the leading cause of long term disability. Almost half of the people living in the community following stroke have problems that challenge the activities that support their daily lives. This is in part due to the rehabilitation community's focus on short term stroke recovery and not on supporting survivors' need to actively manage their long-term disability and the environment around them so they can return to full participation in communities of their choice post-rehabilitation. The rehabilitation community is in need of evidence-based interventions for addressing post-stroke functional limitations. Metacognitive strategy training is a performance-based, problem-solving approach to task performance difficulties. Participants are taught to identify when to apply a cognitive strategy, how to apply it, and how to monitor and adapt usage of cognitive strategies within task performance. Metacognitive strategy training is recognized as a practice standard for addressing functional limitations post-stroke. Transcranial direct current stimulation is a method that has been used for over 15 years to modulate the excitability of targeted brain regions. While it does not directly stimulate neurons, it results in changes to polarity of neuronal membranes and is thought to facilitate or inhibit neuroplasticity. Combination of these approaches may result in an interaction of effects and a greater effect on function in individuals post-stroke than either approach used alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •> 6 months post mild to moderate ischemic stroke
- •self-reported functional limitations
- •Age 30-80
排除标准
- •history of other neurological diagnoses
- •cognitive impairment (less than or equal to 21 on the Montreal Cognitive Assessment)
- •severe aphasia (greater than or equal to 2 on the NIHSS language item
- •non-English speaking
- •any additional condition where the PI deems participation unsafe
- •pregnancy, 7)
- •history of seizures
- •medications that influence cortical excitability
- •metallic implants above the chest
- •history of welding or metalwork
- •severe depressive symptoms (>21 on Patient Health Questionnaire)
结局指标
主要结局
Semi-Structured Interview
时间窗: after study completion, an average of 5 weeks
A brief interview to gather participant perceptions of the intervention, including their perceived benefit and practicality of the intervention and suggestions for improvement for the intervention.
Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM), & Feasibility of Intervention Measure
时间窗: after study completion, an average of 5 weeks
A brief questionnaire to evaluate participant satisfaction regarding the intervention's acceptability, appropriateness, and feasibility
Client Satisfaction Questionnaire (CSQ-8)
时间窗: after study completion, an average of 5 weeks
Self-report, 8 item measures of intervention acceptability
次要结局
- Performance Quality Rating Scale (PQRS)(Pre-intervention and post-intervention, typically an average of 5 weeks)
- Canadian Occupational Performance Measure (COPM)(Pre-intervention and post-intervention, typically an average of 5 weeks)
研究者
Anna Boone
Anna E. Boone, MSOT, PhD, OTR/L
University of Missouri-Columbia
