Effect of Suicidality on Social Cognition

Recruiting

• Conditions: Major Depressive Disorder; Suicide

• Registration Number: NCT06163612
• Lead Sponsor: Unity Health Toronto

Brief Summary

Major Depressive Disorder (MDD) is a very common illness that is usually treated with antidepressant medication. Depression can be caused by many things such as childhood experiences, genetics, and changes in the way the body and brain function. It is most likely caused by a combination of several of these factors. The prevalence of suicide attempt in Major Depressive Disorder (MDD) is about 20%. Risk for suicide attempt can be increased by many things such as negative life events, genetics, and changes in the way the body and brain function. It is most likely caused by a combination of several of these factors.

In this study, the investigators will be collecting detailed information about participants' psychiatric history and depression symptoms, as well as brain scans. The goal is to use this information to help us determine what predicts suicide attempt history.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-01
• Study First Submitted: 2023-11-22
• Study First Submitted QC: 2023-11-30
• Study First Posted: 2023-12-11
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-09
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
fMRI Markers for Suicide Risk	Through study completion, an average of 1 week	Potential fMRI brain activity for suicide risk using participants' brain scans

Trial Locations

Locations (1)

Unity Health Toronto; 🇨🇦 Toronto, Ontario, Canada