Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning

Not Applicable

Not yet recruiting

• Conditions: This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes; Maternal Hemodynamic; Maternal Positioning During CS

• Registration Number: NCT06857162
• Lead Sponsor: Aswan University

Brief Summary

Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes . Hemodynamic instability, such as hypotension following spinal anesthesia, is a frequent complication and can lead to adverse maternal and neonatal outcomes. Traditionally, after spinal anesthesia, women are positioned supine, sometimes with a slight left lateral tilt to mitigate the risk of aortocaval compression . However, recent studies and clinical observations suggest that delayed supine positioning-keeping the patient in a sitting or semi-sitting position for a period following spinal anesthesiamay improve hemodynamic stability. These alternative positions may help to mitigate the abrupt drop in blood pressure commonly seen after spinal anesthesia by allowing for a more gradual redistribution of blood volume . Understanding the optimal positioning strategy could lead to improved clinical protocols that enhance maternal and fetal safety. By comparing immediate supine positioning with delayed supine positioning (in sitting and semi-sitting positions), this study aims to provide evidence on which positioning strategy offers the best hemodynamic outcomes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-08
• Study First Submitted: 2025-02-26
• Study First Submitted QC: 2025-03-03
• Study First Posted: 2025-03-04
• Last Update Submitted: 2025-03-15
• Last Update Posted: 2025-03-19
• Study Start: 2025-04-25
• Primary Completion: 2025-08-01
• Study Completion: 2025-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 216

Inclusion Criteria

• Pregnant women scheduled for elective cesarean delivery.
• Age between 18 and 40 years.
• ASA (American Society of Anesthesiologists) physical status II.

Exclusion Criteria

• Emergency cesarean delivery.
• Pre-existing cardiovascular disease.
• Severe preeclampsia or eclampsia.
• Multiple pregnancies.
• Known fetal anomalies.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
To compare the incidence and severity of hypotension in immediate supine, sitting, and semi-sitting positions during cesarean delivery.	9 Months

Trial Locations

Locations (1)

Aswan University Hospital; 🇪🇬 Aswan, Egypt