Hemodynamic Adaptation in the Peripartum Period using Impedance cardiography (HAPPI).

Recruiting

Conditions: cardiac burden
childbirth
cardiac output
Delivery
10007521
10026906

Registration Number: NL-OMON54780

Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

- Informed consent
- Being in active labour (defined as progressing cervical dilatation)
o Or currently being induced for labour
o Or planned primary Caesarean section

Exclusion Criteria

- Age <18 years
- Multiple pregnancy
- Preterm labour <32 weeks gestational age (GA)
- Labour after intra-uterine fetal death
- Clinical cardiovascular compromise at moment of recruitment (30 weeks GA)
- Abnormal placentation
- Presence of the following ICG contra-indications, as established by the
manufacturer to decrease measurement accuracy:
o Pacemaker
o Implantable cardioverter-defibrillator (ICD)
o Severe aortic insufficiency

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study outcome is the difference in CO trajectory during labour<br /><br>between the cardiac and non-cardiac group. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study outcomes are differences in the impact of obstetric<br /><br>interventions (e.g. epidural analgesia or assisted delivery) on CO trajectory.<br /><br>In addition to CO trajectory, additional hemodynamic parameters (e.g. heart<br /><br>rate and blood pressure) will be measured.</p><br>