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临床试验/NCT02002507
NCT02002507撤回不适用

Effect of Different Surgical Positions on the Cerebral Venous Drainage: an Ultrasound Study on Neurosurgical Patients

University Health Network, Toronto1 个研究点 分布在 1 个国家开始时间: 2015年1月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
1
主要终点
Jugular venous flow

研究概览

简要总结

Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow between the right and left internal jugular veins in the park bench position. In particular, there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine positions.

详细描述

The different positions used in neurosurgery for better accessibility to the operating field (park bench, prone) can impact cerebral venous drainage due to the effects of internal jugular venous outflow of blood, and may increase intracranial pressure. Excessive neck flexion and rotation in the park bench position, or flexion in the prone position, may lead to kinking or twisting of the internal jugular vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction, and increases in intracranial pressure in postoperative patients. Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed in this position. Thus, we look to measure the internal jugular venous flow at different positions, as there have been few studies looking at this important contributing factor.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult neurosurgical patients who are above the age of 18
  • Patients undergoing neurosurgery requiring general anesthesia and placement in either in prone or park bench position for surgical accessibility

排除标准

  • Lack of informed consent
  • Patients undergoing surgical procedures only in the supine position
  • Patients needing a central venous catheter in the neck

结局指标

主要结局

Jugular venous flow

时间窗: 1 day

One of the following will be compared depending on the position of the patient * Bilateral internal jugular venous flow in supine and prone position * Bilateral internal jugular venous flow in supine and park bench position

次要结局

  • cross- sectional area of internal jugular vein(1 day)
  • doppler velocity of jugular venous flow(1 day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lashmi Venkatraghavan

Dr.

University Health Network, Toronto

研究点 (1)

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