Prevalence of Circulating Parvovirus Genome in Recently Diagnosed Graves' Disease: a Case-control Study
Not Applicable
Completed
- Conditions
- Graves Disease
- Interventions
- Biological: serodiagnosis
- Registration Number
- NCT02798965
- Lead Sponsor
- Centre Hospitalier Universitaire, Amiens
- Brief Summary
Lymphocytic thyroiditis is the most common autoimmune disease, usually affecting young women. Although the aetiology and pathogenesis remain obscure, the most widely accepted hypothesis is an interaction between a genetic predisposition and an environmental trigger factor such as viral infection. Parvovirus infections have been proposed as trigger factors for Hashimoto's thyroiditis and Graves' disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
- Graves' disease :patients treated for Graves' disease, the diagnosis date less than 4 months
- Control : patients cared for nodules or goiter
Exclusion Criteria
- Patients undergoing immunosuppressive therapy including corticosteroids
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Graves' disease serodiagnosis patients with Graves' disease Control serodiagnosis patients with goiter or nodule
- Primary Outcome Measures
Name Time Method prevalence of circulating parvovirus genome Day 0
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU Amiens
🇫🇷Amiens, France