NL-OMON48857
Completed
Phase 4
Effectiveness in knee osteoarthritis of an intramuscular gluteal corticosteroid injection versus an intra-articular corticosteroid injection in general practice: a multicenter pragmatic randomized trial - Knee Osteoarthritis Injection Trial
Huisartsgeneeskunde0 sites140 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Huisartsgeneeskunde
- Enrollment
- 140
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) contacted their general practitioner (consultation and/or repeat pain
- •medication prescription) due to knee osteoarthritis (ICPC L90 or L15 with
- •unequivocal diagnosis of osteoarthritis) during the past five years;
- •2\) aged 45 years and over;
- •3\) symptomatic knee osteoarthritis for at least 3 months prior to enrolment;
- •4\) a minimum score of 3 on the numerical rating scale asking about the severity
- •of knee pain averaged over the last week (0\-10; 0\<\=no knee pain);
- •5\) corticosteroid injection is indicated in this patient;
- •6\) signed informed consent form., If a patient has bilateral knee
- •osteoarthritis, the most painful knee according to the patient will be selected
Exclusion Criteria
- •1\) use of oral corticosteroids;
- •2\) intra\-articular injection in a knee in the previous 6 months;
- •3\) allergy to corticosteroids;
- •4\) local or systemic infection, after recent vaccination with live attenuated
- •5\) diabetes mellitus type 1, diabetes mellitus type 2 on insulin therapy,
- •poorly controlled diabetes mellitus type 2;
- •6\) presence of inflammatory rheumatic diseases (such as rheumatoid arthritis,
- •psoriatic arthritis, spondylartropathies);
- •7\) coagulopathy, use of anticoagulants, use of dual antiplatelet therapy;
- •8\) a history of gastric/duodenal ulcer or a present gastric/duodenal ulcer;
Outcomes
Primary Outcomes
Not specified
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