Effects of Neuromobilization on Median Nerve

Not Applicable

Recruiting

• Conditions: Stiffness; Median Nerve; Neuromobilization
• Interventions: Other: Sham neuro mobilization; Other: Neuro mobilization

• Registration Number: NCT05569395
• Lead Sponsor: Istinye University

Brief Summary

The median nerve is a mixed nerve with motor and sensory functions in the upper extremity. It is observed that the median nerve slides longitudinally during upper extremity movements. However, in entrapment neuropathies (eg, Carpal Tunnel Syndrome), longitudinal displacement of the nerve is partially limited. In addition, the presence of adhesion, fibrosis, and possible scar tissue may cause difficulties for peripheral nerve adaptation in certain positions and movements. This, in turn, can result in the limitation of nerve trunk movements with respect to the surrounding tissues and a reduction in the normal shift of nerve fibers and fascicles relative to each other and to the connective tissues. Any pathology that reduces the normal stretch and slip of the medial nerve produces abnormal tension during extremity movement and the pressure on the nerve increases. This may cause symptoms such as paresthesia, weakness, and pain in the hand. With neuromobilization exercises, the tension and pressure on the median nerve are reduced and the nerve is prevented from being compressed in the carpal tunnel.

Neuromobilization is part of manual therapy and has been reported to be an effective practice for some conditions, including low back pain and carpal tunnel syndrome. The inclusion of neuromobilization in the treatment of patients with carpal tunnel syndrome, cervicobrachial pain, and lateral epicondylitis, in particular, has been associated with a reduction in the degree of pain and disability. Recently, neuromobilization techniques have started to be used in the treatment of nerve compression. These techniques consist of a series of therapeutic active and passive movements aimed at restoring the normal mechanical properties of the nerve during limb movements.

When the literature is examined, there are not many studies that objectively reveal the effects of neuromobilization techniques on nerve elasticity. Shear Wave Elastography is a method that quantitatively reveals the elasticity of tissues by measuring the speed of shear waves formed in the tissues through non-invasive high-frequency ultrasound waves. In recent studies, Shear Wave Elastography has shown promising results in demonstrating the elasticity of peripheral nerves.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-09-15
• Study First Submitted QC: 2022-10-05
• Study First Posted: 2022-10-06
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-15
• Last Update Posted: 2023-05-16
• Study Start: 2023-06-15
• Primary Completion: 2023-06-15
• Study Completion: 2023-07-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Between 18-30 years
• Healthy individuals without any known systemic disease

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Exclusion Criteria

• Those who had an upper extremity such as bone-tendon-muscle operation in the last six months
• Those with a systemic disease such as rheumatoid arthritis, diabetes mellitus
• Those with any neuromuscular disease (such as Multiple sclerosis, myopathy)

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control Group	Sham neuro mobilization	Sham median nerve neuro mobilization group
Study group	Neuro mobilization	Median nerve neuro mobilization group

Primary Outcome Measures

Name	Time	Method
Median Nerve Tension Test	1 week	The test is performed with the participant in supine position with shoulder depression and 90 degrees abduction and external rotation, elbow 90 degrees flexion, forearm in full supination, and wrist and fingers in full extension. Maintaining this position, the elbow is passively extended to test the tension of the median nerve. The test is stopped at the point where the patient feels pain and tension, and the angle formed at the elbow will be measured with a universal goniometer and recorded. The measurement will be repeated 3 times and the average value will be recorded.
Shear Wave Ultrasound Elastography	1 week	Nerve elasticity will be measured by measuring the speed of shear waves formed in the median nerve by means of high frequency ultrasound waves.

Secondary Outcome Measures

Name	Time	Method
Range of Motion	1 week	Wrist flexion and extension will be measured bilaterally with a universal goniometer.
Finger Grip Strength	1 week	Finger grip strength will be measured bilaterally with a pinchmeter.

Trial Locations

Locations (1)

Istinye University; 🇹🇷 Istanbul, Turkey