Exercise training in patients awaiting a liver transplantation: a randomised control trial

Not Applicable

Completed

• Conditions: iver Transplant; Exercise Training; Liver Transplant; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12614000791639
• Lead Sponsor: Mr Matthew Wallen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-25
• Study Completion: 2016-04-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

Candidate for Liver Transplant - as per guidelines proposed by the Transplant Society of Australia and New Zealand for Organ Transplant from Decreased Donors
- Gender - males and females are eligible. The study will endeavor to recruit approximately equal numbers of males and females.
- Age - Individuals aged 18 to 69 years old are eligible. At the Princess Alexandra Hospital, patients are not eligible for a liver transplant following the age of 69 years old due to organ allocation policies.
- Ethnicity - All ethnic groups are eligible for the study. There is likely to be incidental recruitment of participants of Aboriginal or Torres Strait Islander ethnicity.
- Willingness to participate - patients must be willing to be randomized to either the exercise intervention or usual care groups and to adhere to the protocol that they have been assigned.

Exclusion Criteria

- Patients that have previously undergone a liver transplant
- On transplant listing for other organs
- Currently smoking
- Any abnormality during the cardiopulmonary exercise test that indicates that it would be considered unsafe to participate in an exercise training intervention
- Uncontrolled diabetes mellitus
- Orthopaedic and/or neurological limitation to exercise as assessed by the principal investigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Safety (measured as number of adverse events associated with exercise training)[Mid Intervention (4 weeks) and post intervention (8 weeks)];Adherence (measured as attendance and compliance to exercise training)[Mid Intervention (4 weeks) and post intervention (8 weeks)]