Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Assessment of life space measured with the Life Space Questionnaire
研究概览
简要总结
Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. Moreover, existing studies suggest that patients with POAG exhibit more postural sway while standing as measured by a balance platform and also tend to walk more slowly than those who are normally sighted and free of ocular disease. While these disturbances likely influence mobility, there has been little research directly assessing the impact of POAG on mobility. This study will assess the impact of POAG on life space (one aspect of mobility) and will determine whether difficulties with life space are associated with difficulties experienced under conditions of dim lighting.
详细描述
Aim 1: To examine the extent of life space in older adults with POAG using the Life Space Questionnaire and to examine whether life space in persons with POAG is associated with the magnitude of visual field impairment.
Aim 2: To examine difficulties seeing under dim illumination and at night in older adults with POAG using the Low Luminance Questionnaire and to examine whether greater difficulty in seeing under dim illumination and at night is related to the magnitude of visual field loss.
Aim 3: To examine the relationship in older adults with POAG between visual problems seeing under dim illumination and at night (Low Luminance Questionnaire) and their life space (Life Space Questionnaire).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of primary open-angle glaucoma
- •Best-corrected visual acuity of 20/40 or better
- •Spherical refraction within ± 5 Diopters
- •Cylinder refraction within ± 3 Diopters
排除标准
- •History of intra-ocular surgery other than uncomplicated cataract or glaucoma surgery
- •Significant cognitive impairment
结局指标
主要结局
Assessment of life space measured with the Life Space Questionnaire
时间窗: Day one
The Life Space Questionnaire is a 9-item questionnaire that assesses how much a person gets out and about and the spatial extent of the person's typical life space, i.e., what is the usual range of places in which the person engages in activities within the designated time frame. Patients are asked to respond either Yes or No.
次要结局
- Relationship between the Life Space Questionnaire and vision loss(Day one)
- Relationship between the Low Luminance Questionnaire and the Life Space Questionnaire(Day one)
- Assessment of vision under dim illumination and at night using the Low Luminance Questionnaire(Day one)
- Relationship between Low Luminance Questionnaire and vision loss(Day one)
研究者
Lyne Racette
Principal Investigator
University of Alabama at Birmingham