A Protocol to Wean From Noninvasive Mechanical Ventilation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Ventilator Weaning
- Sponsor
- Duan jun
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- The duration of noninvasive mechanical ventilation
- Status
- Terminated
- Last Updated
- 12 years ago
Overview
Brief Summary
The investigators use a protocol to wean from noninvasive mechanical ventilation.
Detailed Description
Design: Prospective, randomized, controlled trial, with 2 groups: study (protocol weaning group) and control (clinicians' order weaning group). Setting: Respiratory Intensive Care Unit (RICU). Subjects: Patients \>18 yr, noninvasive mechanical ventilation \>24 hours. Interventions and measurements: Study group (weaning as the protocol) and control group (weaning as the clinicians' order); recording of clinical variables at admission and during RICU stay, and end-point variables (noninvasive mechanical ventilation day, RICU and hospital stay, RICU mortality. Expected results: the protocol group's noninvasive mechanical ventilation days is less than clinicians' order group.
Investigators
Duan jun
The first affiliated hospital of chong qing medical univercity
Chongqing Medical University
Eligibility Criteria
Inclusion Criteria
- •noninvasive mechanical ventilation \> 24 hours.
- •age \>18 years
Exclusion Criteria
- •severe cerebraI，heart，hepatic and renal faiIure.
- •facial or cranial trauma or surgery.
- •facial abnormalities.
- •recent gastric or esophageal surgery.
- •active upper gastrointestinal bleeding.
- •large amount of sputum with weak cough ability
- •lack of co-operation.
Outcomes
Primary Outcomes
The duration of noninvasive mechanical ventilation
Time Frame: from admission to ICU to discharge from it (average of 4 weeks)
The duration of noninvasive mechanical ventilation was measured from the patients admitted to ICU to discharged from it,an expected average of 4 weeks.
Secondary Outcomes
- The successful weaning rate(from admission to ICU to discharge from it (average of 4 weeks))
- The length of ICU days(from admission to ICU to discharge from it (average of 4 weeks))
- The intubation rate during the study(from admission to ICU to discharge from it (average of 4 weeks))
- The mortality during the study(from admission to ICU to discharge from it (average of 4 weeks))