Contrast Induced Acute Kidney in Patients With Acute Stroke
Overview
- Phase
- Not Applicable
- Intervention
- Radiopaque Media
- Conditions
- Stroke, Acute
- Sponsor
- Nanjing Medical University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Creatinine
- Last Updated
- 8 years ago
Overview
Brief Summary
Computed tomographic angiography (CTA) is recommended for identifying eligible patient with acute ischemic stroke (AIS) to receieve endovascular treatment. We are going to conduct this prospective corhot study to observe if sequential use contrast in CTA examination and in endovascular treatment will cause acute kidney injury.
Investigators
Hai-Bin Shi
Professor
Nanjing Medical University
Eligibility Criteria
Inclusion Criteria
- •All patients who are suspected with AIS.
- •Non-contrast head CT excludes intracranial hemorrhage.
Exclusion Criteria
- •Lacking of pre-CTA Creatinine
- •Lacking of post-angiography Creatinine with 24-48 hours
Arms & Interventions
CTA
Patients with AIS only receieved cerebral CTA exam.
Intervention: Radiopaque Media
CTA+DSA
Patients with AIS receieved cerebral CTA, followed by endovascular treatment with the guidence of digital substration angiography (DSA).
Intervention: Radiopaque Media
Outcomes
Primary Outcomes
Creatinine
Time Frame: within 24h to 48h
Contrast-induced acute kidney injury was defined as a relative increase of 25% or an absolute increase of 0.3 mg/dL (28.2mol/L) in the serum creatinine level at 48 hours following angiography