Contrast Induced Acute Kidney in Patients With Acute Stroke
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Creatinine
研究概览
简要总结
Computed tomographic angiography (CTA) is recommended for identifying eligible patient with acute ischemic stroke (AIS) to receieve endovascular treatment. We are going to conduct this prospective corhot study to observe if sequential use contrast in CTA examination and in endovascular treatment will cause acute kidney injury.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who are suspected with AIS.
- •Non-contrast head CT excludes intracranial hemorrhage.
排除标准
- •Lacking of pre-CTA Creatinine
- •Lacking of post-angiography Creatinine with 24-48 hours
研究组 & 干预措施
CTA
Patients with AIS only receieved cerebral CTA exam.
干预措施: Radiopaque Media (Drug)
CTA+DSA
Patients with AIS receieved cerebral CTA, followed by endovascular treatment with the guidence of digital substration angiography (DSA).
干预措施: Radiopaque Media (Drug)
结局指标
主要结局
Creatinine
时间窗: within 24h to 48h
Contrast-induced acute kidney injury was defined as a relative increase of 25% or an absolute increase of 0.3 mg/dL (28.2mol/L) in the serum creatinine level at 48 hours following angiography
次要结局
未报告次要终点
研究者
Hai-Bin Shi
Professor
Nanjing Medical University