Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial
- Conditions
- Dentin Hypersensitivity
- Interventions
- Procedure: CPP-ACP varnishProcedure: Giomer Varnish
- Registration Number
- NCT06154941
- Lead Sponsor
- Cairo University
- Brief Summary
Dentin hypersensitivity is a drastic problem, which threaten many dental patients. According to the last published systematic review and meta analysis at 2019, the prevalence of dentin hypersensitivity is being 33.5% among the population. Moreover, it was determined that young adults with age range from 18 to 44 years exhibited high percentage (43.9%) of such problem
- Detailed Description
Several approaches to dentin hypersensitivity treatment were proposed to interfere, whether transiently or permanently, with the hydrodynamic theory. These approaches include root coverage and the use of lasers, ions, dentinal sealants, and occluding and nerve depolarization agents, chosen according to the primary cause. There are two major strategies in managing DH; the first is nerve desensitization, and the second is the physical occlusion of the patent tubule. The second approach can be carried out through a wide range of treatment modalities, including the use of proteins, salts or ions to plug the tubules. Many agents introduced are capable of sealing dentinal tubules, and can be used to reduce sensitivity. Of these agents are CPP-ACP varnish and the newly introduced giomer based varnish wilth S-PRG technology
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Participants of both genders aged 18 to 40 years with good oral hygiene, suffering from pain due to dentin hypersensitivity in at least one tooth
-
Taking desensitizing treatment in the last 6 months. (It affects the outcome)
- Taking anti-inflammatory drugs. (It affects the hypersensitivity perception)
- Pregnant females. ( They complain from nausea and repeated vomiting attacks)
- Smokers. (Smoking will affect the oral hygiene and periodontal health)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description CPP-ACP based varnish CPP-ACP varnish - Giomer based Varnish Giomer Varnish -
- Primary Outcome Measures
Name Time Method evaporative test Immediately postoperative, after 1,3 and 6 months using an air blast from a conventional dental unit air-water syringe for 5 seconds.
Thermal Test Immediately postoperative, after 1,3 and 6 months using anaesthetic carpule kept in the refrigerator at 4oC for at least 24 hours till it became ice then it is removed from refrigerator immediately before testing .
Tactile test Immediately postoperative, after 1,3 and 6 months using the tip of a sharp explorer (number 3) to gently scratch the exposed cervical surface in an apico-coronal direction with short strokes.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of Dentistry
🇪🇬Cairo, Egypt