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Clinical Trials/NCT05974072
NCT05974072
Completed
N/A

A Feasibility Study of a Multidisciplinary Treatment for Patients with Chronic Low Back Pain: PAINDOC Study.

University of Barcelona1 site in 1 country41 target enrollmentJanuary 24, 2023

Overview

Phase
N/A
Intervention
Usual Care
Conditions
Chronic Low-back Pain
Sponsor
University of Barcelona
Enrollment
41
Locations
1
Primary Endpoint
Recruitment rate
Status
Completed
Last Updated
last year

Overview

Brief Summary

The present feasibility study aims to evaluate the feasibility and adequacy of a multidisciplinary treatment program as a therapeutic option for patients with chronic low back pain referred to the pain unit of the Hospital Clinic of Barcelona. Secondarily, the present study will also evaluate the effect on pain-related outcomes to estimate the number of needed participants for a full trial.

The main questions it aims to answer are:

  • Is the proposed multidisciplinary treatment feasible and adequate for chronic low back pain patients?
  • Is the proposed multidisciplinary treatment effective in improving pain-related outcomes?

Participants will receive either usual care (pharmacological control) or eight multidisciplinary sessions within two months, composed of therapeutic patient education, mindfulness relaxation, cognitive-behavioural therapy and therapeutic exercise. Besides, participants will be assessed using written questionnaires before and after treatment and two months after treatment.

Researchers will assess the feasibility of the multidisciplinary treatment group and will compare both groups to see if there is any difference in several pain-related outcomes.

Detailed Description

Despite improving pharmacological and surgical medical treatment options, long-lasting low back pain is the most frequent pain disorder and a leading cause of disability. Over the past decades, clinicians have acknowledged that a broader view of disease and disability is needed in chronic conditions treatment. Therefore, biological, psychological and social factors must be addressed to improve such conditions. The present study aims to evaluate the viability and adequacy of a multidisciplinary treatment program (PAINDOC Program) as a therapeutic option for patients with chronic low back pain referred to the pain unit of the Hospital Clínic of Barcelona. The secondary objectives are to evaluate the effect of the PAINDOC Program on the reduction of pain intensity, the improvement of pain-related disability, the improvement of quality of life, and the reduction of pain catastrophizing.

Registry
clinicaltrials.gov
Start Date
January 24, 2023
End Date
November 1, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Marc Terradas Monllor

Principal Investigator

University of Vic - Central University of Catalonia

Eligibility Criteria

Inclusion Criteria

  • Patients with primary chronic low back pain (non-specific chronic low back pain).
  • Predominantly axial pain, for at least 50% of the time during the last 6 months.
  • Average pain intensity equal or greater than 4 out of 10 on a verbal numerical scale, during the present week.
  • Predisposed to receive an active, non-pharmacological and non-surgical treatment.

Exclusion Criteria

  • Inflammatory low back pain.
  • History of cancer in the past 5 years.
  • Unexplained and involuntary weight loss of 10 Kg during the last year.
  • Problems in the control of bowel and bladder function.
  • Difficulty attending sessions due to severe physical disability.
  • Diagnosis of severe mental illness (schizophrenia, major depression, bipolar disorder, etc.).
  • Addiction disorder to parenteral drugs or strong prescription opioids. Technical-logistical problems (inability to attend treatment sessions, inability to complete evaluation questionnaires).
  • Seeking compensation or litigation in the last year.
  • Severe hearing loss or severe cognitive impairment.

Arms & Interventions

Usual Care (Pharmacological Control)

The subjects in the control group will be treated following a pharmacological approach according to the latest clinical guidelines for patients with chronic low back pain. Thus, the pharmacological options to be considered in each patient will be those included in the first and second analgesic steps of the WHO (preferably without including minor opioids).

Intervention: Usual Care

PAINDOC Program

The PAINDOC Program is a multidisciplinary treatment that integrates four parts provided by different health professionals and consists of 8 sessions carried out in the pain unit of the Hospital Clinic of Barcelona over two months. It consists of a therapeutic education (Empowered Relief) session given by a physician from the unit, a pain psychology session given by a psychologist, an introductory mindfulness meditation session given by an advanced practice nurse, and two pain neuroscience education sessions and three therapeutic exercise sessions given by a physiotherapist. This program is already part of the pain unit's routine care practice, so it is considered that the sessions of this program do not represent an additional and specific visit for the patients.

Intervention: PAINDOC Program

Outcomes

Primary Outcomes

Recruitment rate

Time Frame: 4 months prior to study start

To obtain this information, the number of participants included in the program for four consecutive months will be calculated. The number of eligible participants, the number of participants included and excluded, and the reasons for exclusion will be detailed.

Number of participants completing treatment

Time Frame: 2 months

Acceptable compliance has been defined as at least 80% of participants included in the program completing all program sessions.

Follow-up rate

Time Frame: 4 months

to determine the follow-up rate, the number of participants who complete the evaluations at each evaluation point in the study will be detailed.

Acceptance of treatment and detection of barriers

Time Frame: 2 months

Treatment acceptance will be assessed through a qualitative approach, based on focus groups and content analysis. The study will have a phenomenological approach to understand and know directly the experiences of the participants. The research will be conducted from the interpretive paradigm, as it seeks to understand and interpret the deep meaning of the observed phenomena. In addition, it is based on an inductive methodology that starts from reality to generate theories, so the fieldwork does not start from a hypothesis.

Secondary Outcomes

  • Pain Catastrophizing. Changes from baseline to 2 months after treatment.(Baseline, 2 months, 4 months)
  • Pain Intensity. Changes from baseline to 2 months after treatment.(Baseline, 2 months, 4 months)
  • Health-related quality of life. Changes from baseline to 2 months after treatment.(Baseline, 2 months, 4 months)
  • Pain-related disability. Changes from baseline to 2 months after treatment.(Baseline, 2 months, 4 months)

Study Sites (1)

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