Emergency Medical Services and Epilepsy in Switzerland

Completed

• Conditions: Epilepsy

• Registration Number: NCT03346382
• Lead Sponsor: Theusinger Oliver M.

Brief Summary

Retrospective data analysis, all emergency medical services of the city of Zurich interventions due to epileptic convulsions during June 2013 and December 2014 have been analyzed regarding the type of drug used, its application mode and the application mode based success. Furthermore, children versus adults were compared. Continuous variables were summarized as mean ± standard deviation (SD) and also presented as median \[minimum; maximum\]. Groups were compared using the independent samples t-test. P-values \< 0.05 are considered significant.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-03-01
• Primary Completion: 2015-12-31
• Study Completion: 2016-06-30
• Status Verified: 2017-11
• Study First Submitted: 2017-11-02
• Study First Submitted QC: 2017-11-14
• Last Update Submitted: 2017-11-14
• Study First Posted: 2017-11-17
• Last Update Posted: 2017-11-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 584

Inclusion Criteria

• emergency calls for epileptic seizures received by the emergency medical system of Zurich,Switzerland,
• the use of midazolam or diazepam or no drug used.

Exclusion Criteria

• the use of any other first line drug to stop seizures than the two mentioned above e.g. thiopental

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Which drug (Midazolam versus Diazepam) better stops epileptic seizures in the pre-clinical setting	follow up up to 1 year	In this retrospective trial, all Emergency Medical Services of the city of Zurich interventions due to epileptic seizures during June 2013 and December 2014 are analyzed regarding the two drugs (Midazolam or Diazepam) used, its application mode (intravenous, nasal, intramuscular, rectal) and the application mode based success. Data will be collected regarding these aspects in order to determine if one drug is better than the other one, and which application mode is the most efficient.; Furthermore, children versus adults are compared. Continuous variables are summarized as mean ± standard deviation (SD) and also presented as median \[minimum; maximum\]. Groups are compared using the independent samples t-test. P-values \< 0.05 are considered significant.

Secondary Outcome Measures

Name	Time	Method
Does the way of application of the drugs (Midazolam versus Diazepam) used in pre-clinical epileptic seizures influence the outcome	follow up up to 1 year	In this retrospective trial, all Emergency Medical Services of the city of Zurich interventions due to epileptic seizures during June 2013 and December 2014 are analyzed regarding the two drugs (Midazolam or Diazepam) used, its application mode (intravenous, nasal, intramuscular, rectal) and the application mode based success. Data will be collected regarding these aspects in order to determine if one drug is better than the other one, and which application mode is the most efficient.; Furthermore, children versus adults are compared. Continuous variables are summarized as mean ± standard deviation (SD) and also presented as median \[minimum; maximum\]. Groups are compared using the independent samples t-test. P-values \< 0.05 are considered significant.