Can Tendon Autograft Function As a Meniscal Transplant

Not Applicable

Completed

• Conditions: Meniscectomy

• Registration Number: NCT06858943
• Lead Sponsor: Cairo University

Brief Summary

Purpose: To evaluate the functional outcomes after using peroneus longus (PL) tendon autograft as meniscal transplantation in patients with knee joint line pain exaggerated with weight bearing following prior total or subtotal meniscectomy.

Detailed Description

This research design is a single center prospective study carried out at a tertiary trauma center hospital between May 2022 and December 2022. This research had ethical Committee Approval which was granted by the Ethics Committee of Cairo University (Institutional Review Board (IRB) number N 207-2024). All patients signed an informed consent before joining this study. This study included 25 patients, with previous history of subtotal or total meniscectomy medially or laterally, who underwent meniscus transplantation using PL tendon autograft.

Study Timeline

• Study Start: 2022-05-01
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31
• Study First Submitted: 2025-02-28
• Study First Submitted QC: 2025-02-28
• Status Verified: 2025-03
• Study First Posted: 2025-03-05
• Last Update Submitted: 2025-03-06
• Last Update Posted: 2025-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Skeletally mature patients with a history of prior subtotal or total (medial or lateral meniscus) meniscectomy.
• Post meniscectomy symptoms (medial or lateral knee joint line pain exaggerated with weight bearing).

Exclusion Criteria

• Multi-ligamentous knee injuries.
• Skeletally immature patients.
• Significant osteoarthritic changes on radiographs (Ahlbäck II- V).
• Malalignment on full-length radiographs showing increased stress in the involved knee compartment.
• Presence of associated ipsilateral ankle joint problem.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Lysholm knee score	baseline, 2 years postoperative	functional knee score, minimum is zero, maximum value is 100, a higher score means a better outcome
Knee Injury and Osteoarthritis and Outcome (KOOS) score	baseline, and 2 years postoperative	osteoarthritis knee score, minimum is zero, maximum is 100, higher score means a better outcome

Trial Locations

Locations (1)

Faculty of Medicine, Cairo University; 🇪🇬 Giza, Cairo, Egypt