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临床试验/NCT04144114
NCT04144114已完成不适用

The Effect of ProHydrolase® on the Amino Acid, Intramuscular Anabolic Signaling, and Endocrine Response to Resistance Exercise in Trained Males

Deerland Enzymes2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2018年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
2
主要终点
Amino acid absorption

研究概览

简要总结

To examine the amino acid absorption following acute resistance exercise between three supplemental treatments: 1) Whey Protein + ProHydrolase (WPH) 2) Whey Protein (W) and 3) Non-Caloric Placebo (PL). To examine three supplemental treatments (WPH, W, PL) in conjunction with acute resistance exercise on the mTORC1 complex pathway. To examine three supplemental treatments (WPH, W, PL) in conjunction with acute resistance exercise on circulating concentrations of endocrine biomarkers.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Triple (Participant, Care Provider, Investigator)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • • At least one-year of resistance training experience
  • Free of any physical limitations (determined by health and activity questionnaire).
  • Between the ages of 18 and
  • Ability to leg press a weight equivalent to 1.5 times their body mass

排除标准

  • • Inability to perform physical exercise (determined by health and activity questionnaire)
  • Taking any other nutritional supplement or performance enhancing drug (determined from health and activity questionnaire).
  • Physical injury preventing the athlete from participating in offseason training
  • Any chronic illness that causes continuous medical care

研究组 & 干预措施

Whey + ProHydrolase®

Experimental

Subjects received 250mg of ProHydrolase® along with 25g of whey protein mixed in a drink every visit for 4 weeks

干预措施: ProHydrolase® (Dietary Supplement)

Placebo

Placebo Comparator

Subjects received 25g maltodextrin in a drink every visit for 4 weeks

干预措施: Placebo (Dietary Supplement)

Whey

Active Comparator

Subjects received 25g whey protein in a drink every visit for 4 weeks

干预措施: Whey protein (Dietary Supplement)

结局指标

主要结局

Amino acid absorption

时间窗: 4 weeks

To examine the amino acid absorption following acute resistance exercise between three supplemental treatments: 1) Whey Protein + ProHydrolase (WPH) 2) Whey Protein (W) and 3) Non-Caloric Placebo (PL)

mTORC1 pathway

时间窗: 4 weeks

To examine three supplemental treatments (WPH, W, PL) in conjunction with acute resistance exercise on the mTORC1 complex pathway

Endocrine markers

时间窗: 4 weeks

To examine three supplemental treatments (WPH, W, PL) in conjunction with acute resistance exercise on circulating concentrations of endocrine biomarkers.

次要结局

未报告次要终点

研究者

发起方
Deerland Enzymes
申办方类型
Industry
责任方
Sponsor

研究点 (2)

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