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Effect of allopurinol in preventing kidney damage due to coronary angiography

Not Applicable
Conditions
contrast induced nephropathy.
X-ray contrast media
Registration Number
IRCT2015120525372N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
200
Inclusion Criteria

All patients undergoing elective PCI
Exclusion criteria: Patients who are candidates for CABG or primary PCI; Patients with gout or prior use of allopurinol; Serum creatinin >3mg/dL or eGFR<60ml/min; Advanced hepatic failure; Patients who are using azathioprine, 6MP, or warfarin; Patients who have not filled/signed consent form, or the ones who had shown adverse reaction to the drug in prior use

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum cystatin C. Timepoint: 24 hours after PCI. Method of measurement: blood sample.;Serum creatinin. Timepoint: 24 hours after PCI. Method of measurement: blood sample.
Secondary Outcome Measures
NameTimeMethod
Serum uric acid. Timepoint: 24 hours before and after PCI. Method of measurement: blood sample.
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