Does Placenta Pathology Predict Outcome of Neonates With Hypoxic Ischemic Encephalopathy?"

Completed

• Conditions: Asphyxia Neonatorum

• Registration Number: NCT03284528
• Lead Sponsor: University Children's Hospital, Zurich

Brief Summary

The histology of the placenta of newborn infants with perinatal asphyxia and hypoxic-ischaemic encephalopathy is analysed. There will be an evaluation if placenta could be a biomarker for neurodevelopmental outcome at 18-24 months of age.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01-01
• Primary Completion: 2017-01-01
• Study Completion: 2017-01-01
• Status Verified: 2017-09
• Study First Submitted: 2017-09-13
• Study First Submitted QC: 2017-09-13
• Study First Posted: 2017-09-15
• Last Update Submitted: 2017-09-20
• Last Update Posted: 2017-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

all newborn infants with APGAR <5 at 10minutes, pH<7.0, lactate >12mmol/L, base excess >16, resuscitation >10min after birth, gestational age >35 weeks and an encephalopathy -

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
neurodevelopmental outcome at 18-24 month of Age	7 years	The investigators will analyse if there is a correlation of placenta histology and neurodevelopmental outcome

Trial Locations

Locations (1)

University Children's hospital Zurich; 🇨🇭 Zurich, Switzerland