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Clinical Trials/NCT03973801
NCT03973801
Completed
Not Applicable

Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS)

Vanderbilt University Medical Center1 site in 1 country12 target enrollmentAugust 19, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neonatal Abstinence Syndrome
Sponsor
Vanderbilt University Medical Center
Enrollment
12
Locations
1
Primary Endpoint
Percent of eligible patients enrolled
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study will assess the feasibility of implementing auricular acupressure as an additional non-pharmacologic therapy for neonates at risk for developing neonatal abstinence syndrome (NAS) at Monroe Carrell Jr Children's Hospital at Vanderbilt University Medical Center (VUMC).

Detailed Description

NAS is a condition in which newborns experience withdrawal symptoms as a result of in utero exposure to opioids and/or other substances ingested by the mother. The condition has significantly risen over the past 20 years. First line treatments for NAS involve the maximization of non-pharmacologic therapies. NAS management focuses on reducing or eliminating the need for medication management to prevent further developmental complications, promote maternal bonding, and reduce hospital length of stay. Auricular acupuncture has been used for the treatment of addiction and has demonstrated efficacy in the adult population. Current evidence suggests that acupuncture is safe and beneficial for multiple conditions that impact neonatal and pediatric populations including NAS. Acupressure is a less invasive therapy and may serve as an additional non-pharmacological adjunct to ease the severe discomfort of withdrawal in neonates at risk for NAS. This study will assess the feasibility of implementing auricular acupressure as an additional non-pharmacologic therapy for neonates at risk for developing neonatal abstinence syndrome (NAS) at Monroe Carrell Jr Children's Hospital at Vanderbilt University Medical Center (VUMC).

Registry
clinicaltrials.gov
Start Date
August 19, 2019
End Date
September 16, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Heather Jackson

Associate in Anesthesiology, Division of Pain Medicine

Vanderbilt University Medical Center

Eligibility Criteria

Inclusion Criteria

  • 37 weeks gestational age or greater
  • Maternal age 16 or older
  • Substance exposure in utero including opioids, illicit drugs, or other medications that cause neonatal withdrawal

Exclusion Criteria

  • Birth trauma
  • Neonatal asphyxia
  • Maternal or neonatal infection
  • Congenital abnormalities
  • Requiring Neonatal Intensive Care Unit (NICU) care

Outcomes

Primary Outcomes

Percent of eligible patients enrolled

Time Frame: end of study enrollment (about 12 weeks)

Percent of patients prematurely terminating treatment

Time Frame: hospital discharge (about 48-72 hours after delivery)

Percent of missing medical record data

Time Frame: hospital discharge (about 48-72 hours after delivery)

Percent of participants completing all study assessments

Time Frame: hospital discharge (about 48-72 hours after delivery)

Percent of data collection procedures completed

Time Frame: hospital discharge (about 48-72 hours after delivery)

Secondary Outcomes

  • Client Satisfaction Questionnaire (CSQ*) Score(Day of discharge (about 48-72 hours after delivery))
  • Percent of providers enrolled in 3 day training course for NADA protocol(Prior to start of study enrollment (May 31, 2019))
  • Percent of providers receiving NADA certification(Prior to start of study enrollment (May 31, 2019))
  • Percent of providers receiving credentialing(Prior to start of study enrollment (May 31, 2019))
  • Intervention Appropriateness Measure (IAM) Score(Day of hospital discharge of baby (about 48-72 hours after delivery))
  • Acceptability of Intervention Measure (AIM)(Day of hospital discharge of baby (about 48-72 hours after delivery))
  • Feasibility of Intervention Measure (FIM)(Day of hospital discharge of baby (about 48-72 hours after delivery))
  • Percent of providers completing 3 day training course for NADA protocol(Day 3 of training)
  • Percent of providers completing clinical competency with NADA protocol(Prior to start of study enrollment (May 31, 2019))

Study Sites (1)

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